AI-Guided Structural Hypothesis Formation: The Oxygen Octave as a Case Study in Human–AI Coherence-Assisted Thinking (CAT)

Abstract (Index version)

This document presents a transparent and falsifiable methodology for AI-assisted scientific hypothesis formation, using the Oxygen Octave as a worked case study.

The approach — Coherence-Assisted Thinking (CAT) — treats human intuition and general-purpose AI systems as a coupled reasoning loop, where hypotheses are iteratively generated, stress-tested, refined, and publicly documented.

Rather than proposing a new physical theory, the work demonstrates how structured interaction with AI can produce a coherent, auditable, and testable scientific hypothesis under strict transparency constraints.

The Oxygen Octave serves as a controlled domain due to oxygen’s well-characterized behavior across chemistry, physics, and biology, enabling rapid detection of structural inconsistencies or hallucinations.

All reasoning steps, intermediate failures, data sources, and revisions are preserved through public versioning, allowing independent replication, critique, and extension.

[Read full methodology and technical details on Zenodo]

Jaime Ojeda

Comenzó su trayectoria en 2007, trabajando en un brewpub en Chicago. Su sed de conocimiento lo llevó a estudiar en el Siebel Institute of Technology/World Brewing Academy, perfeccionando sus habilidades y conocimientos.

Ha participado en diversos paneles de cata y prestigiosas competencias a nivel internacional, entre las que se incluyen el World Beer Cup, Brussels Beer Challenge, Copa Cervezas de América, Copa de Cervezas de Brasil, South Beer Cup, entre otros . Su talento y paladar experto le han valido reconocimiento en el mundo cervecero.

En 2008, creó el portal ConEspuma.com con el objetivo de educar y promover el consumo responsable de cerveza. Su compromiso con la difusión del conocimiento cervecero ha dejado una huella en la comunidad.

Hoy en día, trabaja como consultor independiente, brindando su valiosa experiencia a empresas y emprendedores que desean sobresalir en la industria cervecera.

https://conespuma.com/
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From Zero to Open Question: A Controlled Stress Test of Human–AI Scientific Reasoning Under Maximum Transparency Constraints

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The Oxygen Ladder: Minimal Geometric–Electronic Rearrangement as an Organizing Principle for Oxygen Chemistry