From Zero to Open Question: A Controlled Stress Test of Human–AI Scientific Reasoning Under Maximum Transparency Constraints

Abstract (Index version)

This document establishes the methodological and epistemic foundation of the Oxygen Octave Project and the Coherence-Assisted Thinking (CAT) framework.

It documents a controlled experiment exploring whether a non-expert, working under strict transparency and falsifiability constraints, can use general-purpose AI systems to construct and refine a coherent scientific question.

Oxygen was selected as a case study due to its exceptionally well-characterized behavior across chemistry, physics, and biology, allowing structural inconsistencies and hallucinations to be readily detected.

Rather than presenting a scientific hypothesis, this work defines the constraints, reasoning loops, failure modes, and documentation standards of an openly auditable AI-assisted research process.

The document serves as the methodological origin of the project and frames failure itself as a scientifically valuable outcome when fully documented in real time.

[Read full methodology on Zenodo]

Jaime Ojeda

Comenzó su trayectoria en 2007, trabajando en un brewpub en Chicago. Su sed de conocimiento lo llevó a estudiar en el Siebel Institute of Technology/World Brewing Academy, perfeccionando sus habilidades y conocimientos.

Ha participado en diversos paneles de cata y prestigiosas competencias a nivel internacional, entre las que se incluyen el World Beer Cup, Brussels Beer Challenge, Copa Cervezas de América, Copa de Cervezas de Brasil, South Beer Cup, entre otros . Su talento y paladar experto le han valido reconocimiento en el mundo cervecero.

En 2008, creó el portal ConEspuma.com con el objetivo de educar y promover el consumo responsable de cerveza. Su compromiso con la difusión del conocimiento cervecero ha dejado una huella en la comunidad.

Hoy en día, trabaja como consultor independiente, brindando su valiosa experiencia a empresas y emprendedores que desean sobresalir en la industria cervecera.

https://conespuma.com/
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The Oxygen Octave – Foundations: Quantitative Correlations Across Vibrational Systems

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AI-Guided Structural Hypothesis Formation: The Oxygen Octave as a Case Study in Human–AI Coherence-Assisted Thinking (CAT)